"GCT" meaning in All languages combined

See GCT on Wiktionary

Noun [English]

Forms: GCTs [plural]
Head templates: {{en-noun}} GCT (plural GCTs)
  1. Initialism of germ cell tumor. Wikidata QID: Q1737977 Tags: abbreviation, alt-of, initialism Alternative form of: germ cell tumor Hypernyms: tumor, neoplasm, mass
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          "text": "Under these provisions, the germ cell theory paradoxically implies that the biologically more indolent germinomas arise from the most undifferentiated germ cells, whereas the most malignant forms of GCTs (choriocarcinoma and yolk sac tumor) arise from highly differentiated germ cells. That, and the notion that the germ cell theory employs parthenogenesis in humans, and the lack of a plausible explanation of the mechanism through which primordial germ cells mismigrate to the cranial cavity, led to its challenge by Sano and colleagues who proposed the alternative \"embryonic cell theory.\" This suggests that a mismigrational pluripotent embryonic cell (i.e., a stem cell at the blastocyst stage, past the stage of a totipotent stem cell) gives rise to intracranial GCTs.¹¹ Contrary to the germ cell theory, which advocates that all types of GCTs arise from a common cell of origin (primordial germ cell), the embryonic cell theory suggests the involvement of multiple embryonic cells of various stages of embryogenesis.",
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This page is a part of the kaikki.org machine-readable All languages combined dictionary. This dictionary is based on structured data extracted on 2026-07-09 from the enwiktionary dump dated 2026-07-06 using wiktextract (e62056b and e7887d5). The data shown on this site has been post-processed and various details (e.g., extra categories) removed, some information disambiguated, and additional data merged from other sources. See the raw data download page for the unprocessed wiktextract data.

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